The decision to undergo joint replacement surgery is a big one. One must take into account the possibility of serious, potentially life-threatening complications that commonly occur. Besides the danger, there is also a significant amount of down time, particularly with weight bearing joints (like the knee or hip), and even more so if there is infection, prosthetic rejection or further surgeries. One of the best things about regenerative medicine is the procedure is not only minimally invasive (and therefore much safer), but there is literally no down time. Even with multiple injections performed in the same day, most patients are able to drive themselves back home and continue to work and perform their daily activities. Depending on the joint involved, there may be some mild restrictions to ensure maximum benefit from the treatment, however there are no periods of complete incapacitation. While stem cell recruitment products seem to be most active within the first 90 days, they often continue activating tissue and improving joint space for the following six months to a year. The 12 week rehabilitation is also an extremely important aspect of the treatment and should be taken into account when planning for this procedure.